GPCR assay  


Our established biochemical assays enable measuring affinities and kinetics of label-free ligand-GPCR interaction. The assays leverage carefully optimized solubilization conditions that allow production of monodisperse GPCR particles. Available for CXCR4, CXCR7, CCK2, NTSR1, ADRB2, NOP, chimeric MOR and NK1. Please contact us for a quote. If you don't find your GPCR assay among the established one, we are happy to discuss feasibility of a customized solution


We recently published with our customer Merck KGaA the use of FCCS to support the identification of Methionine Aminopeptidase-2 (MetAP-2) inhibitor M8891.
https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b01070


See our new publication on the quantifiaction of target occupancy in tissue:
https://doi.org/10.18632/oncotarget.22801


Check out our new GPCR-ligand interaction assay!